What causes osteoarthritis?
Though osteoarthritis is caused by wear and tear to the joint over time, there are certain factors that make some patients more likely to develop the condition. For example, genetics can play a role; some patients have a rare defect that interferes with the body’s ability to produce collagen — the protein that makes up cartilage. Other genetic conditions can affect how the bones in the body fit together, increasing stress on the cartilage.
In addition, patients who participate in sports, physical activities, or hold occupations that require repetitive joint movements are at a higher risk of developing osteoarthritis. Some athletes, especially those who repeatedly damage their joints, are at very high risk, as are patients who work jobs that require repetitive bending or lifting.
Further, being overweight can put additional pressure on the joints, causing the cartilage in the hips and knees to break down faster than it should. Some studies also suggest that excess fat tissue can produce inflammatory chemicals that cause the joints to break down.
The most common causes of osteoarthritis include:
- Wear and tear
- Obesity
- Genetics
- Menopause
- Repetitive motions
Source:
Arthritis.org